Drug Levels Maternal Levels. The major metabolite of spironolactone, canrenone, was measured in the serum and milk of a day postpartum woman who was taking 25 mg of spironolactone four times daily. The authors estimated that the nursing infant would receive about 0. Relevant published information was not found as of the revision date. Effects in Breastfed Infants In day-old breastfed extent not stated infant whose mother was taking 25 mg of spironolactone 4 times daily since pregnancy, serum sodium and potassium remained normal. She was also taking mg of bretylium tosylate every 8 hours, atenolol 25 mg daily, propranolol 20 mg 3 times a day, and multivitamin, potassium and magnesium supplements.
Spironolactone (Oral Route) Before Using - Mayo Clinic
Spironolactone and Pregnancy Back to Top Tell your doctor if you are pregnant or plan to become pregnant. The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. Spironolactone falls into category C. In animals studies, pregnant animals were given this medication and had some babies born with problems. There are no well-controlled studies that have been done in humans with spironolactone, though.
Is spironolactone (Aldactone) safe for pregnant or breastfeeding women?
Medical uses[ edit ] Spironolactone is used primarily to treat heart failure , edematous conditions such as nephrotic syndrome or ascites in people with liver disease , essential hypertension , low blood levels of potassium , secondary hyperaldosteronism such as occurs with liver cirrhosis , and Conn's syndrome primary hyperaldosteronism. The most common use of spironolactone is in the treatment of heart failure. The classification of spironolactone as a "potassium-sparing diuretic" has been described as obsolete. For this reason, it is frequently used to treat a variety of dermatological conditions in which androgens play a role. Some of these uses include acne , seborrhea , hirsutism , and pattern hair loss in women.
Drug information provided by: IBM Micromedex In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: